Faculty Info: Simona Bartl
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SIMONA BARTL Adjunct Professor, Moss Landing Marine Laboratories B.S., University of California at Davis Ph.D., University of California at San Diego Email: sbartl@mlml.calstate.edu Lab Website: http://invert.mlml.calstate.edu Teacher Enhancement Program: http://teach.mlml.calstate.edu |
Specific Research Interests: My research falls into three categories. First, I have a long-standing interest in the evolution of the adaptive immune system. I study the molecules involved in immunity in cartilaginous fishes and protochordates. Second, I am interested in using molecular techniques to find previously unattainable answers to questions in marine biology. In particular I am looking at species identification in bivalves. Third, I am working with middle and high school teachers to bring a better understanding of scientific research and SMT (science, math, technology) concepts to their students. Current Projects: (1) Immune systems of fishes; (2) Evolution of immune molecules; (3) Invertebrate host defenses; (4) Molecular biology techniques; (5) Teaching the scientific method; (6) Teaching SMT skills and concepts. Selected Publications: Bartl, S., Cagampang, H., and H. Kibak. 2005. Teaching information technology in context: Marine biotechnology and bioinformatics for teachers. In: Proceedings of Society for Information Technology and Teacher Education International Conference 2005. AACE, Norfolk, VA. pp. 3068-3073 Bartl, S., Miracle, A. L., Rumfelt, L. L., Mochon, E., Litman, G. W., and M. F. Flajnik. 2003. Terminal deoxynucleotidyl transferases (TdTs) from elasmobranchs reveal structural conservation within vertebrates. Immunogenetics 55:594-604 Bartl, S., Baish, M., Weissman, I. L., and M. Diaz. 2003. Did the molecules of adaptive immunity evolve from the innate immune system? Integrative and Comparative Biology 43:338-346 Rumfelt, L. L., Avila, D., Diaz, M., Bartl, S., McKinney, E. C., and M. F. Flajnik. 2001. A shark antibody heavy chain encoded by a nonsomatically rearranged VDJ is preferentially expressed in early development and is convergent with mammalian IgG. Proceedings of the National Academy of Sciences, USA 98:1775-1780 Bartl, S. 2001. New Major Histocompatibility Complex class IIB genes from nurse shark. In: Phylogenetic Perspectives on the Vertebrate Immune System. G. Beck, M. Sugumaran, and E. Cooper, eds., Kluwer Academic/Plenum Publishers, New York, pp. 1-11 Ohta, Y., Okamura, K., McKinney, E. C., Bartl, S., Hashimoto, K., and M. F. Flajnik. (2000) Primitive synteny of vertebrate major histocompatibility complex class I and class II genes. Proceedings of the National Academy of Sciences, USA 97:4712-4717 Bartl, S. 1998. What sharks tell us about the evolution of MHC genes. Immunological Reviews 166:317-332 Bartl, S., Baish, M. A., Flajnik, M. F. and Y. Ohta 1997. Identification of class I genes in cartilaginous fish, the most ancient group of vertebrates displaying an adaptive immune response. Journal of Immunology 159:6097-6104 Kepler, T. B. and S. Bartl 1997. Plasticity under somatic mutation in antigen receptors. In: Current Topics in Microbiology and Immunology, Vol. 229, Somatic Diversification of Immune Responses. G. Kelsoe and M. F. Flajnik, eds., Springer-Verlag, Berlin, pp. 149-162 Bartl, S. 1997. Amplification using degenerate primers with multiple inosines to isolate genes with minimal sequence similarity. In: Methods in Molecular Biology, Vol. 67, PCR Cloning Protocols: From Molecular Cloning to Genetic Engineering, B. A. White, ed., Humana Press, Inc., Totowa, NJ, pp. 451-457 Bartl, S., and I. L. Weissman. 1994. Isolation and characterization of major histocompatibility complex class IIB genes from the nurse shark. Proceedings of the National Academy of Sciences, USA 91:262-266 |
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